By Scott A., Prof. Snyder

The speedy velocity of evolution in domino, or cascade-based adjustments has revolutionized the perform of chemical synthesis for the production of average items, designed molecules, and pharmaceuticals.


"Science of Synthesis: purposes of Domino variations in natural Synthesis" explores the subject completely and systematically, serving because the foundation for sensible functions and destiny examine. The 2-volume set offers the state-of-the-art when it comes to layout, technique, and experimental techniques, resulting in a number of occasions being comprehensive inside a unmarried response vessel. The content material is equipped via the center form of response used to start up the development, be it a pericyclic response, a metal-mediated transformation, radical chemistry, or an acid-induced cascade between many others.


Volume 1 covers polyene/cation-pi cyclizations, metathesis, radical, and metal-mediated reactions, and non-radical skeletal rearrangements.

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