By Richard A. Kahn

For the 1st time specialists within the zone of signalling examine with a spotlight at the ARF family members have contributed to the creation of a identify dedicated to ARF biology. A accomplished phylogenetic research of the ARF kin, tables of the ARF GEFs and ARF GAPs, and greater than a dozen chapters describing them intimately are supplied. The influence of the ARF proteins on generally varied facets of mobile biology and mobile signalling may be truly obvious from the actions defined; together with membrane site visitors, lipid metabolism, receptor desensitization, mouse improvement, microtubule dynamics, and bacterial pathogenesis. an individual attracted to figuring out the complexities of cellphone signalling and the combination of signalling networks will make the most of this volume.

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